The Best just got better


The MS-350 medical pouch sealer machine has been the gold standard for over 20 years. This year the best got better with a host of system upgrades to better serve your sterile packaging plan. ce-marking mark available.

Medical Pouch Sealer – Decorate Your Cleanroom

This medical pouch sealer utilizes a powerful, direct-drive electronic solenoid to deliver seal to seal force consistency for repeatable sealing. A thin film thermocouple sends thermal data from the sealing environment to finely manage sealing performance. Our medical device packaging machines are designed to be gentle on consumable parts for a low cost of ownership. Our simple step menu easily guides users through the setup process for rapid pouch changeovers. Our pouch sealers are delivered from our ISO 17025 accredited laboratory for accurate calibration for our ISO 13485 medical device manufacturing customers. For years Van der Stähl Scientific machines have sealed billions of pouches through our network of worldwide users.


Our robust, solenoid actuated sealing bar engenders seal to seal force by gating voltage through our advanced microprocessor. With our airless system you do not need to manage the complexities of validating the air source. Just plug into a power outlet and you’re ready to package your medical device.


Some of our MS-350 medical pouch sealing machine customers have had their sealers for years and counting. Built on a heavy-duty base-plate with precision componentry, the MS-350 sealers are built for the long haul. Over a billion seals are made on our sealers each year worldwide, join our list of satisfied customers.


Our sealers ship to you from our fully accredited ISO-17025 calibration lab. We perform temperature calibrations at multiple internal thermal zones for better accuracy. Our optional “Pro calibration” certifies time output and checks the mechanical system’s force with a multi-zone force calibration.
MS-350 Medical Pouch Sealing Machine

MS-350 Medical Pouch Sealing Machine

The MS-350 medical device pouch sealer has been the industry standard for over 20 years. Easily develop and manage validation limits with verifiable control limits. Installation qualifications are easily defined with our airless, direct-drive solenoid and our available 3-point critical attribute calibrations. Our calibrations are delivered through our ISO-17025 accredited laboratory.


The MS-350 medical pouch sealer machine ships to your doorstep with a free temperature calibration from our ISO-17025 accredited laboratory. Ask about our “Pro Plan” for force, time, and multi-temperature calibration to jump-start your packaging validation.

The sterile barrier system’s best friend

The MS-350 medical device packaging machine creates a 10mm wide seal and can seal a pouch up to approximately thirteen inches wide. The pouch sealers does not require an air supply as force is delivered through a powerful solenoid. The MS 350 sealer can seal a variety of materials such as nylon, Tyvek®, Mylar, foil, and poly. The microprocessor allows for the adjustment of contact temperature, contact time, and release temperature. Set the MS-350 sealer to a semiautomatic mode for touch-free operation, or activate with the foot or hand switch for better user flexibility.

  • Password protected settings
  • Multi-zone internal calibration
  • Adjustable auto-cycle mode
  • Powerful solenoid
  • Airless system operation
  • Easy wipe-down design
MS 350 medical pouch sealer

Airless Force Performs Seal after Seal

A powerful direct drive solenoid develops consistent force onto the medical pouch to engender repeatable seals. The MS-350 microprocessor finely manages electrical force to the solenoid for seal-to-seal consistency. Avoid process and validation risks of air-driven force with our robust solenoid pressure management system.

Sterile Medical Pouch Sealing Performer

The MS 350 medical pouch sealer does not use inexpensive air valves to actuate the critical force at the platen. Our custom-built solenoid is minutely controlled through the system’s advanced microprocessor. The low profile form factor makes an attractive addition to your cleanroom and is well-suited for wipe downs. Our intuitive step function microprocessor makes setup simple.
Medical Pouch Sealer
MS-350 Calibration

Calibration Ready Machine Architecture

The MS-350 utilizes a firmware algorithm with multiple thermal points to enhance range accuracy. Our laboratory developed force capture system, finally assesses machine force. Our “Time Tap” provides an output time signal for system time verification. The MS-350’s multipoint calibration are the headwater to a strong validation.

Medical Pouch Sealing Machine features that matter

Our powerful microprocessor managed solenoid system…

Our precision high force solenoid creates seal to seal accuracy to better manage your critical process. The MS-350 pouch sealer is completely airless and only requires standard voltage for operation. With our new direct drive system, we can achieve greater force to accommodate a wider range of pouch material. We have removed multiple wear parts for longer duty cycles and less scheduled maintenance.

Microprocessor Managed Solenoid Sysem for Medical Pouch Sealer
Thermal performance

Microprocessor delivered electrical gating delivers accurate platen temperature

Thermal Performance
Easy Setup

Intuitive menu steps and paddle keys make machine setup fast, accurate and simple.

Medical Pouch sealer Machine Easy Setup
Environment sensing

Our thin film temperature sensor accurately gathers the platens thermal environment.

Environment Sensing
Total ergonomics

A host of safety and ease of use features including sound dampening for user comfort.

Total Ergonomics

Look Whats included With Your New MS-350 Medical Pouch Sealer

Accredited Calibration

Accredited Calibration

Receive a no cost thermal calibration on your new medical pouch sealer from our ISO/IEC 17025 calibration laboratory.

Certified IQ Support

Certified IQ Support

Let us help you with your “Installation Qualifications” from our staff of skilled quality system certified technicians.

Pouch Integrity Test

Pouch Integrity Test

Receive a no-cost 10 specimen pouch test from our ISO-17025 accredited lab. This study includes robust reporting.

Compliant Documents

Compliant Documents

All included documents and certifications come from our ISO/IEC 17025 accredited pouch test and calibration laboratory.

Accredited Calibration

Accredited Calibration

Receive a no cost thermal calibration on your new medical pouch sealer from our ISO/IEC 17025 calibration laboratory.

Pouch Integrity Test

Pouch Integrity Test

Receive a no cost 10 specimen pouch test from our ISO-17025 accredited lab. This study includes robust reporting.

Certified IQ Support

Certified IQ Support

Let us help you with your “Installation Qualifications” from our staff of skilled quality system certified technicians.

Compliant Documents

Compliant Documents

All included documents and certifications come from our ISO/IEC 17025 accredited pouch test and calibration laboratory.

Medical Pouch Packaging begins with accredited calibrations



When developing your DOE (design of experiments) it is vital that you understand the value of all measured attributes. With our laboratory developed system, we can verify our machinery’s adherence to time set points. Understand all critical points for a stronger I.Q.


The amount of force that is being applied to your pouch needs to be understood to develop a cogent medical device packaging validation. With our precision transducers and advanced meters, we can verify critical machine force, and will provide easy to read reporting.

Thermal Calibration

The best medical device packaging validations are built on a machine calibration that explores the usable range of thermal performance. With our range calibration, we will verify packaging machine compliance at 3 temperatures for a more complete calibration.

Pouch Testing integration, the future of Medical device packaging

Medical device packaging engineers agree the pathway to compliant device packaging is through regular testing and inspection. With our patented MS-451-PV medical device pouch sealing machine, seal performance is verified with the onboard testing and inspection system.

Our customers are talking

"...The Van der Stähl name has become a fan favorite within our metrology department because of the certification Van der Stähl performs on the units. When we receive the machines in, the metrology department needs to do very little to get these active..."


Our customers are talking

"Amazing company to work with. The information is exactly what we need to complete our IQ OQ PQ. Thank you! Your company is a leap above the rest…"


Our customers are talking

"We have found Van der Stähl products and services to exceed our expectations. The sealers, test equipment and calibration services have been robust, efficient, and competitively priced. Van der Stähl is a key contributor to our continued success."


Our customers are talking

"I just wanted to send a quick note to thank you and all the Van der Stahl Scientific team for going above and beyond to resolve the issues we had with our pouch sealer. Even though the issues were not of your doing, you took it upon yourself to make things right so we could meet the commitments that we made to our customers. We were blown away by your response and greatly appreciate you, not only for expediting the build, but for completely replacing the machine!"


Our customers are talking

"High level of customer service by a group of technicians and sales staff that know their product."


Our customers are talking

"Your customer service is even better than the great equipment you provide. Even on the other side of the world I know we can count on your team. We are customers for life. Van der Stähl has the best combination of equipment and people."


Explore other Medical Machine packaging systems

MS-451 medical device pouch sealer

Hybrid sealer

The MS-451 has an integrated peel testing and visual inspection system to help assure compliant seals and ships with a full calibration. An all-in-one medical device packaging solution for device manufacturers to seal, test and inspect their pouches. The system outputs data via USB.
Medical Device Pouch Testing

Testing Systems

Testing and inspecting is one of the single most important quality steps your company can take to avoid a packaging recall. With the PTT-100-V the process of testing and inspection is quick and easy. Learn more about all of our medical pouch testing and inspection solutions.
Rotary Medical Pouch Sealer

Rotary Sealers

With the MD-series packaging machines, the sealing process is managed with tight thermal controls and a highly accurate transducer that monitors sealing force. Fixed pressure and conveyance speed allow for a simple design of experiment. Print and seal with a single step with the MD-series sealer.

Decorate your cleanroom with medical packaging compliance

Your medical device sterile to the point of care

Van der Stähl Scientific has helped thousands of medical device manufacturers deliver their devices safe and sterile to the point of care. We provide advanced microprocessor-controlled medical device pouch sealing machinery to deliver seal-to-seal consistency. With a host of medical device validation support options, you can choose from a selected area of support or a complete end-to-end validation package.


Meet our Six Sigma master black belt, patented inventor and medical device packaging guru, contact Charlie for validation support.

Charlie A. Webb, CPPL

Director of quality, new product development

The master of solutions, our Laboratory, and Service Manager Cord Burnham guides our service, testing and calibration effort.

Cord Burnham CKF

Director of laboratory and Calibration services

Our customers best friend, our General Manager Lisa Wassberg creates magic at every touch point for our medical device clients.

Lisa Wassberg, CKF

General manager, customer relationships

Sarah’s intuitive eye can solve machine issues with ease. Sarah is a Six Sigma Black Belt and understands the critical process.

Sarah Deputy, CKF

Testing and Calibration services

Speak with a Medical Pouch Sealer Machine expert


Skip the salesman and speak with a certified packaging engineer like our support team leader Charlie A. Webb CPP, CKF. Charlie is a certified packaging engineer, a patented innovator and a six sigma master black belt with more than 20 years of sterile packaging experience. Fill out the form below and request a quote or give us a call, we would love to chat…